TOP OF THE WORLD DISTRIBUTORS®

Top of the World Distributors® was founded in February 1997 by Randy and Lisa Roney in Union City, Tennessee. Because of Lisa’s background in nursing, she and Randy both felt compelled to staff the company with health professionals and experts in their field. By doing so, they were able to offer a higher quality customer service by providing competent advice and consultation. It also gave them a greater insight into the types and quality of products that they would like to offer. That’s why each and every product from Top of the World Distributors® has been evaluated and researched to the highest degree to insure safety and effectiveness with no adverse reactions.

Calotren® is a registered trademark of Top of the World Distributors® as is the entire Top of the World Pro Formula® health products line. Calotren® was established in February 2001 and is manufactured in the United States. The formulation for this collagen-based product is based on the heavily-researched protein - collagen hydrolysate – which has been available and on the market for over 25 years.

Calotren® is a nutritional supplement formulated to support your body, maintaining its optimum balance for healthy weight. This collagen protein (collagen hydrolysate) formula is easily digested and supplies your body with very important nutrients to help your body to maintain collagen production while helping to build lean muscle.

Calotren® nutritionally feeds your body, which allows it to support itself in maintaining or increasing your lean muscle tissue, which helps your body to burn fat and sugar more effectively, as well as supporting your body's natural metabolism. Increasing lean muscle tissue allows your body to burn more calories while at rest, so if you don't increase your calorie intake, increased lean muscle tissue can result in burning more calories. For those who are underweight or in good physical condition, Calotren® encourages your body to reach its highest level of vitality, without additional undesirable loss of lean muscle mass, which frequently occurs during calorie-restricted "dieting".

Twenty-four percent of the dry protein weight of the human body is collagen. The primary amino acid in collagen is L-hydroxyproline, a non-essential amino acid. Non-essential does not mean that the human body does not require it for good health. A healthy body, with good digestion and an adequate supply of essential amino acids, can manufacture the required non-essential amino acids.

Remember, fat is stored energy. When we are young we have a faster metabolic rate which assists our bodies in producing energy to build muscle, bone and maintain good health while we sleep. As we get older, this process slows down. Our bodies no longer function in this manner or produce the collagen or amino acids required to keep our skin looking radiant or our bodies tight and strong.

Collagen Hydrolysate is the main ingredient in Calotren®.

Collagen is a protein rich formula containing the following amino acids:
1. Glycine
2. Proline
3. L-Hydroxyproline

Although these are considered non-essential amino acids, they are necessary for proper function and growth of the muscle tissues in the body.

Collagen and reticular fibers contain the protein collagen. Collagen is very tough material and these fibers impart great strength to structures in which they occur (meat is tough because of its collagen content). The tensile strength of collagen has been compared to that of steel. When collagen is hydrolyzed (water is added under a special process changing it to hydrolyzed collagen), collagen is then converted into soluble protein gelatin. Collagen is a fibrous insoluble protein found in the connective tissue, including skin, bone, ligaments and cartilage. Collagen represents about 30% of the total body protein. Without adequate dietary proteins in the body, the body cannot produce antibodies against disease organisms; therefore resistance (immunity) levels are lowered.

When protein intake is inadequate, the liver cannot manufacture sufficient plasma proteins to maintain a balance between the fluids in the blood and tissues. As a result fluid accumulates in the tissues. The recommended daily amount of protein is 58 grams (0.8 grams per Kg of body weight per day) or 25% or the daily diet.

Glycine:
A simple amino acid needed for the synthesis of the hemoglobin molecule. Collagen and glutathoine can be converted to creatine, which is utilized to make DNA and RNA.
1. Useful in healing wounds.
2. Useful in treating manic psychological states.
3. Useful in problems of muscle spasticity
4. Considered useful in reducing gastric acidity.
5. In high dosages, 4-8 grams, glycine stimulates the release of human growth hormones.
6. It is used as a mild sweetener in foods and drugs
7. It is extremely important in brain metabolism: energizing without hyperactivity.

Proline:
1. Main amino acid in collagen.
2. Helpful in the formation and maintenance of bone, skin, and cartilage formation.
3. Found in eggs, dairy products, some meats and wheat germ.
4. Can be created from glutamine and ornithine.
5. Helpful in maintaining healthy joints and tendons: aids in tissue repair following injury and wound healing.

Hydroxyproline:
1. An important component of collagen which makes up the fibrous connective tissue and
is a part of the skin, bones and cartilage.
2. Is converted from proline by hydroxylation only after proline gets into the amino acid
chain that forms body proteins.